We used the claims files to derive information on inpatient and outpatient diagnoses documented as the ICD 9 CM (international classification of diseases, ninth revision, clinical modification) codes, procedures as the Current Procedural Terminology (CPT 4) codes or the Healthcare Procedural Coding System (HCPCS), prescriptions as National Drug Code (NDC), date of services, and days of the prescription supplied. We used the enrollment files to derive information about patients’ demographic characteristics (including year of birth and sex) and monthly medical/pharmacy enrollment indicators.Study populationOur study population included 244872 enrollees with a prescription of warfarin, dabigatran, or rivaroxaban between 1 October 2010 and 31 March 2012. We entered each person into the cohort at the date of his or her first prescription for any of the three study drugs after 1 October 2010.
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