The participation rate was 65% and the subcohort included 5022 women (fig 1). Bone mineral density (BMD, g/cm2) was determined at the hip, at the lumbar spine (L1 L4), and of the total body. Osteoporosis was defined as a T score at either the total hip, femoral neck, or spine of 2.5 standard deviations (SD) below the mean of a young adult reference range.14 The precision error of the bone mineral density measurements, based on triple measurements in 15 participants, varied depending on sites between 0.8% and 1.5%.
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